Centre of Excellence in Microbiome (CoEM)

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Agar Art Competition Prize Distribution
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Agar Art Competition Prize Distribution Winners

Agar Art Competition Prize Distribution Winners- Ms. AthilaNasrin and Ms. Geethu Ajith of St. Xavier’s College for Women, Aluva, won the first and second places. Ms. ANJANA M BABU of Advanced Centre for Regenerative Medicine and Stem cell research in Cutaneous Biology, University of Kerala and Ms. Shelin Jose V, St. Thomas College, Pala received a special mention. CoEM congratulates all the winners and participants.

Scientist Profile

Dr.Aparna Shankar, PhD

Dr.Aparna Shankar Scientist aparnas.6110004@kerala.gov.in/ draparnashankar@gmail.com Dr.Aparna Shankar earned her PhD in Molecular Microbiology from the University of Edinburgh, United Kingdom, in 2017. Her doctoral research illuminated critical aspects of host–pathogen interactions and nutrient dependencies of a gastrointestinal opportunistic pathogen thereby laying the groundwork for potential novel antimicrobial therapies. Following this, she joined the Department of Pathogen Biology at BRIC–Rajiv Gandhi Centre for Biotechnology in Thiruvananthapuram as a Postdoctoral Researcher. There, Dr.Aparna led investigations into the shifts in microbial diversity, antibiotic resistance patterns and its molecular mechanisms of multi-drug-resistant isolates from aquatic biotopes in the post-2018 Kerala flood scenario. The work underscored the importance of One Health–oriented microbial surveillance in post-disaster settings. She also studied the effects of maternal postpartum antibiotic use on the infant gut microbiome through whole metagenome and resistome analysis, generating early evidence for the adoption of strict practices to regulate antibiotic administration aimed at preserving infant microbiome integrity and combating antimicrobial resistance. Furthermore, she was engaged in teaching Biotechnology students at the postgraduate level. Dr Aparna joined the Centre of Excellence in Microbiome as a scientist in January, 2025. She is involved in exploring the potential of plant-soil microbiota and development of a consortia to enhance crop yield and strengthen disease resistance within agricultural systems. Additionally, she is also investigating ways to enhance climate resilience by improving microbe-driven carbon sequestration. Another major focus of interest lies in the validation of Ayurveda and other traditional medicinal systems for their microbiome-modulating health benefits through emerging integrative approaches in research.

Scientist Profile

Dr.Karthika S

Dr.Karthika S Scientist karthika.6110003@kerala.gov.in/ karthikascoem@gmail.com Dr.Karthika has research interests spanning the human microbiome, with an emphasison gut metagenome mining and probiotic product development.She earned Ph.D. from the Rajiv Gandhi Centre for Biotechnology (BRIC-RGCB), Govt. of India, where her work focused on bacterial pathogenesis, biofilm formation, and alternative strategies to control antimicrobial resistance.She has also developed microbial consortia relevant to the coir industry.Her post-doctoral researchfocused on developing human-origin potential probiotic strains capable of producing urolithins, which are gut microbiota-derived metabolites known for their multifaceted health-promoting properties. During her CSIR-Research Associate tenure, she investigated changes in gut microbial diversity pattern in healthy population during interventions via targeted and shotgun metagenomics and focused on gut microbiota derived metabolites.She has expertise in metagenomics and big data analysis. Dr.Karthika joined the Centre of Excellence in Microbiome as a Scientist in January 2025. She is engaged in identifying microbial biomarkers associated with major gastric associated and life style disorders to address health concerns, treatment efficacy and explore prospects for translational microbiota-based therapies. She also focuses on the fermented food microbiome, development of probiotic products, and starter cultures for health benefits. Additionally, she is interested in collaborative projects focused on formulating beneficial microbial consortia for industrial applications.

Scientist Profile

Dr. Mahesh S Krishna

Dr. Mahesh S Krishna Senior Scientist mahesh.6110002@kerala.gov.in/ maheshskrishna@gmail.com Dr. Mahesh S. Krishna completed his PhD in Biotechnology from University of Kerala in 2011.After his Post Doctoral tenure at Prince of Songkhla University, Thailand, and CSIR-RA at National Institute for Interdisciplinary Science and Technology, Dr. Mahesh joined as Fast Track Young Scientist (DST-SERB) at Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram. After a tenure of three years as Assistant Professor at RGCB, he moved to Clout Bio Innovators Pvt Ltd as Chief Technical Officer and Director of Research. He has also received Post DoctoralFellowship from KSCSTE. He joined Centre of Excellence in Microbiome–KSCSTE as Senior Scientist in January, 2025 . He is specialized in the development of microbiome-based products and microbial applications.With extensive experience in translational research, he focuses on harnessing microbial diversity for innovations in health, nutrition, and environmental sustainability. Dr. Mahesh is in charge of the product development and entrepreneurial support activities in different domains of microbiome. One of the major research areas focussed by Dr.Mahesh is in the validation and development of microbiome based probiotic products. This includes the development of microbiome-assisted feed formulations designed to enhance immunity, improve feed conversion ratios (FCR), and mitigate antimicrobial resistance in the poultry and aquaculture industries. He is also investigating on new process that lead to syngas/hydrogen production through fermentation, coupled to advanced clean and green energy generation. His work bridges fundamental microbiome science with real-world outcomes to benefit public health and industry.

Facilities

Startup Facilities

MICROBIOME STARTUP SUPPORTING PROGRAM Centre of Excellence in Microbiome (CoEM), a premier institution working in the field of microbiome, is initiated by the Govt. of Kerala under the aegis of KSCSTE. The major focus of CoEM is to create a strong knowledge base in the area of microbiome and to disseminate the knowledge for the development of products, technologies and measurable outcomes for the benefit of society. PURPOSE AND PROCESS CoEM extends structured incubation support to selected microbiome-based startups, with a focus on transforming innovative concepts into market-ready products. Startups at the Proof-of-Concept stage may apply by submitting an application as per format, outlining their profile, required support, and a basic workplan with achievable milestones in a 11-month period. To safeguard intellectual property, applicants are advised to sign a Non-Disclosure Agreement (NDA). Applications will undergo committee evaluation, following which selected firms will be invited for a discussion. Inducted teams may start with a three-month pre-incubation program upon payment of a nominal bench fee (see payment options below). Performance during this phase will be closely monitored and evaluated by CoEM. Subsequent extension of support will be contingent on evaluation report. Startups inducted to CoEM will also benefit from industry-connect initiatives, enabling direct interaction with leading industrial partners. This provides them with valuable exposure to current industrial challenges, emerging opportunities, and sector-specific requirements in the microbiome domain, thereby aligning their product development with market relevance. WHAT WE OFFER FULL FLEDGED LAB FACILITIES IN PLUG AND PLAY MODE ADVANCED EQUIPMENT FACILITY AMBIENT CO-WORKING SPACE EXPERT SCIENTIFIC MENTORING, IF REQUIRED AUDIO-VISUALLY EQUIPPED MINI SEMINAR HALL WIFI CONNECTIVITY CONDUCIVE ENVIRONMENT FOR MICROBOIME BASED STARTUPS PAYMENT PACKAGES MONTHLY RENT FOR SITTING SPACE: Rs. 2000/- PACKAGE FOR BASIC LAB FACILITY: Rs. 8000/- pm Basic lab package includes the usage* of: Microbial culture facility Basic lab equipments Minimum storage space in -20 and -80 deep freezers Seminar hall of 25 pax capacity (3 meetings per month) Scientific mentoring support** (one meeting per month) Entry cards Wifi access THREE-MONTHS PRE-INCUBATION PACKAGE: Rs. 6000/- per month. This include Rs. 2000 as sitting space rent and Rs. 4000 as basic lab package. *Shared facility; Pre-booking is mandatory ** If required and subjected to NDA ACCESS TO ADVANCED EQUIPMENTS* This includes the usage of: PCR Animal cell culture facility Phase Contrast microscope Gel documentation unit Inverted microscope Lyophiliser Multi-mode reader Anaerobic Culture Facility Support firms to utilise facilities such as Genomics, Metagenomics and advanced analysis, Proteomics, Metabolomics and advanced imaging services through outsourcing. *On payment basis; Pre-booking is mandatory; Use of advanced equipments will be supported/supervised by staff of CoEM Connect us at Ph. 8138999099 Email: coemkscste@gmail.com  

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