Phytomicrobiome comprising bacteria and fungi are integral to plant nutrition and stress resistance towards biotic/abiotic factors thereby dictating plant growth and productivity. A diverse array of microbes thrives in the rhizosphere and play crucial role in nutrient conversion, disease resistance and overall plant physiology. CoEM is committed to explore the plant-microbial interactions of indigenous plants and crop varieties of Kerala inhabiting diverse geographical locations, especially the Western Ghat region. The application of bio-inoculants in agriculture promotes more organic farming and can be made more effective by understanding the complex network of plant interactions through microbiome research. Such precise studies can provide insights into tackling drought scenarios, food shortage and climate and earth system models thereby exerting a positive outcome on the crop productivity and overall wellbeing of the society. Delving deeper into the microbiome will also aid plant health by enabling their ability to assist in the production of antimicrobial compounds, detoxification, nutrient uptake and growth promoting activities.